WebMar 1, 2011 · TLR3 expression by tumors dictates the antitumor efficacy mediated by dsRNAs in vitro and in immunodeficient mice Based on these clinical data, we evaluated in vitro and in preclinical animal models whether the antitumor effect of dsRNA is mediated by TLR3 expressed by tumor cells. WebTLR3 is a pattern recognition receptor that participates in innate immune response to microbial pathogens by recognizing polyinosine-polycytidylic acid (Poly(I:C)) and dsRNA. Ligand binding by TLR3 induces receptor dimerization which results in inducing NF-κB activation (via TRIF-linked RIP1/TLR3 interactions) and cytokine production.

Mouse Toll Like Receptor 3 ELISA kit

WebDescrizione: Rat anti Tubulin Alpha:HRP: Applicazioni: IHC-Fr, WB, ELISA: Reattività: Yeast, Dictyostelium discoideum, Dendraster excentricus, Clytia sp., Canine ... WebTLR3 functions as a receptor for double-stranded (ds)RNA typically associated with viral infection (4). It was originally shown to be specifically expressed in dendritic cells of the … dubai tour package from bangalore

Anticorps monoclonaux Antibodies.com

WebAnti-TLR3 Chicken Polyclonal Antibody FUNCTION: Participates in the innate immune response to microbial agents. May be involved in the recognition of ds-RNA. Acts via … WebMar 17, 2015 · Among the chicken (Ch) TLR family, ChTLR3 and 7 have been shown to recognize viral RNA. In our earlier studies, we have reported polymorphisms of TLR1, 2, … WebTLR3 belongs to the Toll-like receptor family which are important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA. dubai trade type of declaration