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Labchip® low pi charge variant analysis

WebVersatile instrument for protein analysis and quantitation Multiple assays available for quantification, molecular weight sizing, purity, charge variants and glycan analysis. With our pre-verified assays, there is no (or little) method development needed. WebThese multi-use chips are designed to run 96 sample in a single experiment. Each chip can be used to analyze 500 samples. These chips come in two variants: low pI for acidic …

Low pI Charge Variant Assay Quick Guide LabChip GXII Touch

WebThese automated assays will analyze each protein sample in 60 seconds and can run 96 samples per experiment. This assay comes in two variants: low pI and high pI to fully … WebNov 1, 2011 · Analyzing charge variants of therapeutic proteins is critical for characterizing and monitoring quality attributes of antibodies. Charge variants include deamidation, formation of N-terminal pyroglutamate, aggregation, isomerization, sialylated glycans, antibody fragmentation, and glycation at the lysine residues. In some cases, such … reflecting strips https://pkokdesigns.com

LabChip® High pI Charge Variant Analysis PerkinElmer

WebCharge variant analysis is a widely used analytical tool in characterization of monoclonal antibodies (mAbs). It depicts the heterogeneity of charge variant forms, some of which may differ by only minor modifications of a single amino acid. The analysis ensures product consistency with no unwanted changes to the protein. WebThe PerkinElmer LabChip charge variant analysis chips allow you to screen and analyze the charge variant profiles of protein samples fast and easily on LabChip GXII Touch™ HT … Webinterest - from the ProteinEXact™, Protein Express, Pico and Low Molecular Weight assays for concentration, molecular weight sizing, and percent purity for each detected peak within the sample; in addition, rapid Glycan Screening and Charge Variant analysis can be performed on the same system. reflecting sound waves

LabChip GXII Touch HT Protein Characterization System

Category:LabChip GXII Touch HT Protein Characterization System

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Labchip® low pi charge variant analysis

Imaged Capillary Isoelectric Focusing for Charge-Variant Analysis …

WebLow pI Charge Variant Assay Quick Guide LabChip ® GXII Touch Sample Preparation 1. (Recommended) If the protein sample contains cell culture media, salt (>10mM), … WebCapillary isoelectric focusing (cIEF) is a high-resolution analytical technique that allows the separation of protein/peptide mixtures, protein glycoforms and other charge variants, based on their isoelectric point (pI). cIEF is based on the principle of …

Labchip® low pi charge variant analysis

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http://www.caliperls.com/assets/031/9367.pdf WebpI and charge profiles allows selection of the mAb that most closely reflects a developer’s specific attributes of interest. Table 4. Theoretical and Experimental pI values of main charge variants determined by cIEF Note: Main peak pI and % species vary based on capillary condition, reagents, instrument, method, and integration parameters.

WebThe LabChip® GXII Touch™ protein characterization system offers rapid quantification and quality control throughout biotherapeutics and genomic workflows. For example, … WebThe LabChip ® Extended Range N-Linked Glycan assay is ideal for rapid screening of N-linked glycan profiles by combining: Plate based reagents in 96-well format for convenience and ease of use in automated liquid handlers such as the JANUS® G3 workstation from PerkinElmer. Rapid enzymatic deglycosylation with PNGase F in 96 well format.

WebA Low pI Charge Variant Assay User Guide PerkinElmer, Inc. Preparing the Chip 1Allow the chip to equilibrate to room temperature (20 - 25°C) for at least 30 minutes before use. … WebThe LabChip ® GXII Touch ™ protein characterization system provides the complete solution for reproducible quantitation, molecular weight sizing and percent purity analysis of protein samples. Leveraging microfluidic electrophoretic separation technology, the LabChip ® GXII Touch ™ system enables rapid characterization with minimal sample preparation …

WebThe Protein Charge Variant Assay is for use with the LabChip GXII Touch instrument. LabChip GXII Touch instruments are for research use only and not for use in diagnostic procedures. Preparation Procedures 6 PN CLS140162 Rev. C Protein Charge Variant Assay User Guide PerkinElmer, Inc. Preparation Procedures Additional Items Required

WebLabChip® GX Touch™ microfluidic technology offers comprehensive analysis of nucleic acids and proteins. Generates reproducible data with high resolution. A wide portfolio of Protein Assay chips to meet the required parameters Rapid analysis of … reflecting statementsWebThe PerkinElmer LabChip charge variant analysis assays allow you to efficiently analyze the charge variant profiles of your protein samples. reflecting systemsWebHT Protein Charge Variant Kit User Guide _____ Caliper - a PerkinElmer Company Page 3 of 18 PN: CLS135474 Rev. 02 68 Elm Street Hopkinton, MA 01748-1668 1-877-LABCHIP (1-877-522-2447) Kit Contents HT Protein Charge Variant Kit (P/N: CLS760670) Items at -20 ºC reflecting sunlight on solar panelsWebPerkin Elmer LLC LabChip Low pI Charge Variant Analysis Supplier: Perkin Elmer LLC CLS154134 The PerkinElmer LabChip charge variant analysis assays allow you to … reflecting surface curves inwardreflecting surface is bulged outWebLabChip GXII Touch assays with this chip. Thoroughly clean the electrodes of the instrument with water (Milli-Q ® or equivalent) before placing the chip in the instrument if the Protein … reflecting targetWebThe PerkinElmer LabChip charge variant analysis assays allow you to efficiently analyze the charge variant profiles of your protein samples. reflecting target type i for curb