WebSmall cell lung cancer (SCLC) represents about 13%–15% of all lung cancers. It has a particularly unfavorable prognosis and in about 70% of cases occurs in the advanced … WebAs SCLC is at diagnosis an exceptionally chemoresponsive disease, patients with poor performance status attributable to disease may substantially improve with the initiation of …
KMT2C deficiency promotes small cell lung cancer metastasis
Web16 Dec 2024 · SCLC originates from neuroendocrine cells and is characterized by a rapid growth and high metastatic potential. It commonly responds to both chemotherapy (ChT) and radiotherapy, with a response rate (RR) of around 70–80%. WebAll patients with systemic clinical manifestations at diagnosis suffered from extended disease. Our SCLC patients were older than never-smoking lung cancer patients included … roots country market manheim
SCLC - Rare Disease Day 2024
Web1 Nov 2024 · Small Cell Lung Cancer (SCLC) is the most common neuroendocrine tumour of the lung [] and accounts for 10% of all lung cancers [].Its incidence is associated with smoking, almost two thirds of patients present with advanced disease [], and although response rates to chemotherapy are high, the benefit is short-lived.With platinum and … Web21 Apr 2024 · Given the global chromosome remodeling and gene regulation along the metastasis trajectory of SCLC (Extended Data Fig ... the emerging concept that SCLC is a highly heterogeneous disease 15,36 ... The main treatment for extensive stage disease is chemotherapy with or without immunotherapy. Your doctor might also suggest radiotherapy to the brain to reduce the risk of cancer spreading there. Instead of radiotherapy to the brain, they might suggest observation through routine MRI scans. See more Doctors describe small cell lung cancer as limited if the cancer is contained in a single area on one side of the chest. And the cancer can be treated with … See more Extensive disease means that the cancer has spread beyond a single area that can be treated with radiotherapy. It might have spread: 1. within the chest … See more Staging using limited and extensive disease is becoming less common. Doctors are using the TNM and number staging systems more regularly. This is because … See more The TNM staging system stands for Tumour, Node, Metastasis. 1. T describes the size of the tumour 2. N describes whether there are any cancer cells in the lymph … See more roots country market pa